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This suggests that some of the mechanisms that repress neurogenesis in old brain might stay irreversible

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2025, doi: 10.1056/NEJMoa2502081

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KB-141 (3,5-dichloro-4-(4-hydroxy-3-isopro-pylphenoxy) phenylacetic acid) is another THR-selective agonist with clinical relevance, as it has been shown to reduce cholesterol in rats whose diet was supplemented with cholesterol and cholic acid