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Its extreme local potency, coupled with the systemic risks inherent to IGF-1 (such as potential tumor acceleration and long-term changes in glucose regulation), means its use should be strictly confined to controlled research settings with rigorous safety monitoring

While individual outcomes vary, research and clinical experience provide a reliable range that can help set realistic expectations

As GLP-1 RAs are contraindicated for people with gastrointestinal disease, pancreatitis, or a family history of mutations in multiple endocrine neoplasia type 2/medullary thyroid carcinoma (MEN2/MTC), SGLT2i is the preferred treatment for these patients groups

For constipation, increase fiber intake and drink plenty of water

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