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For the reaction 0.4 l of this solution was added to 19.6 l of 15 M solution of Janus Kinase 3 (MBS2097317, MyBioSource) in 20 mM Tris at pH 8.0 with 150 mM NaCl and 2 mM MnCl 2

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As shown in Figure 7 , in mock- and GSTP1 -transfected HepG2 cells dose- and time- dependent up-regulations of CHOP-GFP signal were detected following treatment with AQ-QI or DEAQ-QI

That will help scientists paint a more realistic portrait of the drugs strengths and weaknesses as treatments for different diseases