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Establishment of 143B subcutaneous osteosarcoma mouse model and therapeutic effect evaluation Tumor model establishment and biodistribution study of NP4 in vivo Three female BALB/c nude mice were subcutaneously inoculated with 143B human osteosarcoma cells (3 10 6 ) on the right buttock

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Multiomics tools for improved atherosclerotic cardiovascular disease management

Glutathione, known as the master antioxidant, is produced by the body and plays an important role in various cellular processes 1

With respect to alpha-1 antitrypsin deficiency, whose patients are at high risk of developing emphysema, introducing a normal copy of its corresponding gene known as SERPINA1 that carries several mutations might lead to the expression of functional alpha-1 antitrypsin to protect lung tissue against neutrophil serine proteinases, especially neutrophil elastase [220]

doi: 10.1186/s12964-025-02121-2 97 BersukerKHendricksJMLiZMagtanongLFordBTangPHet al