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Regulation and function of neurogenesis in the adult mammalian hypothalamus

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In contrast, age-related mitochondrial changes are associated with reduced HSPA9 expression and decreased ERmitochondria membrane coupling, leading to impaired protein degradation and diminished mitochondrial calcium uptake (Acquarone et al., 2025)

273 In addition, in a rat model of inflammatory OA induced by monoiodoacetic acid (MIA), researchers have shown that the activation of GLP-1R triggers the PKA/CREB signaling pathway, leading to a reduction in cartilage inflammation

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