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Promotion of NLRP3 activity by oxidative stress is likely to play a prominent role in a wide range of poorly understood inflammation-related conditions, such as myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), long COVID, Alzheimers disease, and other disorders associated with aging

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Patients with acute injuries, severe pain, loss of function, swelling, neurological symptoms, or other concerning changes should seek appropriate in-person medical evaluation

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