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Piatek et al., 2020

Blood oxytocin is crucial to start uterine muscle contractions during childbirth

This post notes that most GLP-1 administration falls in the 29G to 31G range, with lengths generally between 4 mm and 8 mm, because the medication has to reach the fatty layer beneath the skin rather than muscle

Indomethacin can cause a decrease in renal function when combined with triamterene

A more conservative approach may be worth discussing with a provider if you have a history of GI sensitivity or conditions like IBS, have previously stopped GLP-1 therapy because of side effects, are an older adult (who may be more sensitive to GI effects), or are starting treatment at a lower BMI where the full therapeutic dose may not be necessary