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Paleness may appear before other symptoms because B12 impacts red blood cell production

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In recent years, research has increasingly focused on the mechanism of ferroptosis in patients with depression

Nitrous oxide, a commonly used anesthetic, oxidizes and inactivates vitamin B 12 , thus inhibiting both of the vitamin B 12 -dependent enzymes, and can produce many of the clinical features of vitamin B 12 deficiency, such as megaloblastic anemia and neuropathy

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