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Such physiological clearance mediated by the hair-like cilia on the surface of epithelial cells with their fluctuating movement is responsible for the clearing of nasally administered drugs from the nose with a half-life of 21 min (Ozsoy et al., 2009)

So NACs timing isnt arbitrary

At Kwelio, we build systems that fix both sides of that equation: Clinically dosed, bioavailable formulations that match biology with design

Always use dosing guidelines specific to the arginate formulation

However, reaching these doses needs careful titration over 20 weeks to minimize gut side effects