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Increased cyclic AMP-dependent protein kinase activity in postmortem brain from patients with bipolar affective disorder

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PubMed Ugwu SO, Blanchard J, Dorr RT, Levine N, Brooks C, Hadley ME, et al

Although NAC co-exposure was not able to compensate for THC-induced GABA reductions, it normalized relative DA content, spontaneous EPSCs frequency, gamma power and behavioural abnormalities, underscoring the relevance of excitation/inhibition balance and its sensitivity to oxidative stress in these phenomena

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