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Patients often describe a floating or unsteady feeling rather than true rotational vertigo

Bouchard et al., 2023)

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Due to the compounds plasma half-life of approximately 3.86.9 hours, twice-daily (BID) dosing may provide more sustained NNMT inhibition

This limitation highlights the need to pair such therapies with agents that promote epithelial repair and balanced mucin production such as cystic fibrosis transmembrane regulator modulators, growth factors or emerging mucosal regenerators to fully restore airway defence and function 251,252

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