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Treatment of the second aliquot with TCEP and IAM, followed by measurement of CAM-S-CAM-TPP after protein precipitation, gave the total amount of RSS /RS(S) n S present in the tissue homogenate, giving values that are consistent with earlier reports of overall tissue levels of persulfides using sulfane sulfur atom trapping 31,32

Supplied as a 50 mg lyophilized peptide with full COA traceability

Microbiome 12:275

PubMed: 41549912 Kreider RB, et al

Cheng F, Desai RJ, Handy DE, Wang R, Schneeweiss S, Barabsi AL, et al

By inhibiting autophagy and inducing mitochondrial ROS, TMAO activates NLRP3 inflammasome, leading to the release and pyroptosis of IL-1/IL-18 dependent on caspase-1 in colon epithelium, which is a hallmark of IBD severity