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The representative synthetic compound targeting Nrf2 is melatonin, an amine hormone secreted by the brains pineal gland [203]

That means it activates GLP-1 receptors involved in appetite, insulin response, and digestion

Diets high in saturated fats and processed foods can lead to increased inflammation and oxidative stress, while diets rich in antioxidants like vitamins C and E, zinc, selenium, and omega-3 fatty acids help protect sperm from oxidative damage

Risks and Side Effects of IGF-1 LR3 While IGF-1 LR3 is generally well-tolerated, some individuals may experience mild side effects, such as muscle soreness, fluid retention, hypoglycemia, or insulin resistance

Plasma MOTS-c rises acutely following high-intensity interval training and correlates with improvements in VO2 max and insulin sensitivity post-exercise [2]

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