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doi: 10.3390/nu13010196 36
First, optimal dosing in humans remains undefined, with current practice based primarily on extrapolation from animal studies and anecdotal clinical experience rather than formal dose-finding studies
Through the 1980s and 1990s, research expanded to cover wound healing, skin remodeling, and collagen synthesis
Site rotation: Systematically rotate injection sites between abdomen (at least 2 inches from navel), outer thighs, and upper arms to reduce local irritation and prevent tissue hardening [8]
Yet the effect aspect in this part of the triad has been more elusive
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