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J.BuckleyP.SeaboltW.MellorA.KirkpatrickB
PMID: 22107186 [6] Smart N, et al
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FOXO4-DRI: Senolytic Peptide Mechanism and the p53-FOXO4 Axis FOXO4-DRI is a D-retro-inverso peptide that selectively kills senescent cells by disrupting the protective FOXO4-p53 interaction
Physiological Basis The delay in gastric emptying induced by GLP-1 receptor agonists (GLP-1 RAs) arises from a coordinated modulation of gastrointestinal motility under central vagal control
He points to shifting consumer priorities as validation
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