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10.1152/ajpregu.2001.281.3.R839 Am

HCQ and CQ exert their immunomodulatory effects by inhibiting TLR7 and TLR9 signaling, which plays a crucial role in the pathogenesis of autoimmune diseases such as SLE (101103)

Oligodendrocytes may, akin to astrocytes, exploit fatty acidderived acetyl-CoA for ketone body production within the cholesterol biosynthetic pathway, either through the action of 3-hydroxy-3-methylglutaryl-CoA lyase or via the direct deacylation of acetoacetyl-CoA (Auestad et al., 1991)

Research also demonstrates effects on other neurotrophins including Nerve Growth Factor (NGF) and GDNF (Glial cell line-Derived Neurotrophic Factor)