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For intraperitoneal or other routes, use appropriate needle gauges

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Some researchers believe this activation may lead to an increased release of inositol triphosphate (IP3) and diacylglycerol (DAG)

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IGF-1 is a member of a family of growth factors that are structurally closely related to pro-insulin and can promote chondrocyte proliferation, enhance matrix production, and inhibit chondrocyte apoptosis