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Despite our use of a large, comprehensive data source, this study had some limitations

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Collectively, our findings demonstrate that adding GLP-1RA to SGLT2i therapy is a promising therapeutic strategy for patients with MASLD and T2D, offering significant improvements in mortality, liver outcomes, and kidney protection

Journal of Biological Chemistry 281, 24756-24768CrossRefGoogle ScholarPubMed 25Dinkova-Kostova, A.T., Holtzclaw, W.D., Cole, R.N

Based on these initial studies and comprehensive characterization, liraglutide was selected as having the best properties, combining high receptor potency with pharmacokinetics (PK) that are optimum for OD dosing (43)