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3 Discussion APL presents with severe clinical manifestations, with high risks of bleeding and embolism during onset and induction therapy, potentially leading to fatal outcomes

Vesicular release, mediated by VAMP3, is regulated by Ca 2+ signaling [350]

10.1073/pnas.2022790118 Proc Natl Acad Sci USA

[11] [12] Often called Rboh, for respiratory burst oxidase homolog [13] Note that HO- production is also possible in the chloroplast lumen and in the mitochondrial intermembrane space

Correlation among insulin binding, degradation, and biological activity in human breast cancer cells in long-term tissue culture

CSF levels of heat shock proteins Hsp65 and Hsp70 have been found to be increased (Fiszer et al., 1996), and PD patients have shown higher HLA-DR expression in CSF monocytes in comparison with controls (Fiszer et al., 1994a)