All authors made substantial, direct and intellectual contribution to the work, and revised the manuscript
196 Administration of anti-obesity medications alone, without incorporating lifestyle treatments limits effectiveness and fails to provide the lifelong changes needed to promote weight maintenance
Deters, B
If the remaining Phase 3 readouts hold and the FDA filing proceeds on the projected late- 2026 timeline, retatrutide is positioned to arrive as the unambiguous class leader and the first obesity drug whose efficacy curve starts to genuinely overlap with bariatric surgery
To find the lowest effective dose for maintaining their achieved target weight, we gradually decrease the dose and reduce the frequency of dosing, she told Healthline
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