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One of the main actions of berberine is to activate an enzyme inside cells called AMP-activated protein kinase (AMPK), according to some animal studies ( AMPK plays a key role in regulating metabolism and energy levels and is found in cells throughout your body ( Berberine also affects other molecules inside cells and may even affect which genes are turned on or off

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(Phila.) 60 (4), 472477 (2022)

This is why thorough clinical trials are essential to evaluate the safety and efficacy of peptides before they are approved for human use

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This ratio of GSH: GSSG is maintained by the action of GSSG reductase, which requires NADPH+ as the reducing cofactor