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Reminder: Retatrutide remains investigational it is in Phase 3 trials (TRIUMPH program) and is not approved for human use as of 2026

EXAMPLE 3: Development of Antiotensin IV Analogs as Hepatocyte Growth Factor/Met Modifiers The 6-AH family [D-Nle-X-Ile-NH-(CH 2 )5-CONH 2

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This study showed that chemogenetic activation of NTSVTA projections decreased consumption of a high fat diet (HFD) in drug-nave mice 28

None of which replace Phase 2 safety and efficacy data in human subjects

Further studies can help to elucidate the age, gender or speed of progression of hair loss, which is most responsive to the TRX2 treatment