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Severe gastroparesis (delayed gastric emptying) is a caution or contraindication for some GLP-1 medications, as these drugs further slow gastric emptying and may exacerbate symptoms

The first experiment asked whether a dual GLP-1/GIP agonist (tirzepatide, the active ingredient in Mounjaro) causes outsized muscle loss in obese mice

The myofascial pain may even originate in areas far removed from the active trigger point, leading to what is known as referred pain

It provides the corresponding bioequivalence with reduced amount of drug, which is 1.5 mg, 4 mg, and 9 mg of semaglutide, respectively [48]