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When you're eating significantly less which many GLP-1 users do, especially in the early weeks protein is what keeps your body from losing muscle mass along with fat

The large intestine and upper gastrointestinal tract are rarely affected

The Mechanism of Action of GLP-1 Medications Understanding how GLP-1 medications work can shed light on their effectiveness

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Mechanisms of Action-Mediated DDIs Furthermore, assessing DDIs for GLP-1 RAs and a dual GLP-1/GIP RA requires additional considerations, including the possible occurrence of DDIs mediated by mechanisms of action that remain poorly understood (Figure 3)

Important note: If you are taking insulin or sulfonylureas, talk to your provider about low blood sugar risk before starting tirzepatide