Using biodegradable polymeric nanoparticles (NPs) engineered for TAM targeting via CD206 mannose receptor binding, researchers delivered in vitro -transcribed mRNA encoding IRF5, a transcription factor crucial for M1 polarization, and its activating kinase, IKK
Of note, a recent investigation showed that Sec24C interacts with SLC6A14, a member of the solute carrier family, and promotes its vesicular trafficking to the PM [40]
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