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To adjust for the possibility that the treatment reduced Buchnera numbers, we performed dPCR for a region of a control gene ( rne encoding ribonuclease 3)

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In addition, Ab#2_DSB#1 displayed equivalent terminal half-life in mice based on Fc detection and GLP-1R activity (Supplementary Table 4) with no significant loss of peptide activity for at least 7 days (Fig