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In case blood samples were further processed for a scRNA-seq, a density gradient centrifugation was then conducted using Histopaque 1077/1119 (Sigma-Aldrich) following the manufacturers protocol

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2 Since SLC25A39 protein is expressed in various tissues including the postnatal brain (see for details e.g.,: this may hint for a specific role of that carrier in mitochondrial activity of certain neuronal populations

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For more information regarding homocysteine and CVD, see the article on folate

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