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When we don't get enough iron, we may experience: Reduced capacity to exercise and skeletal muscle atrophy, even before iron deficiency anemia (IDA) develops Over time, IDA, resulting in abnormal red blood cell formation and symptoms such as fatigue, weakness, difficulty concentrating, impaired cognitive and immune function, and poor body temperature regulation IDA has also been linked to impaired glucose metabolism---potentially due to poor conversion of proinsulin to active insulin in the body

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There are multiple HDIs in clinical development and key representatives are shown in Figure 1C

Unfortunately, theres no specific cutoff value regarding how much ammonia is safe

1,6 As a consequence, they do not possess specific structural integrity, making it difficult to target them

Daly EJ, Trivedi MH, Janik A, et al