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This rhythm influences wakefulness and sleep patterns, but when the HPA axis becomes dysregulated, it can lead to symptoms like trouble falling and staying asleep, as well as daytime fatigue (or feeling wired and tired)

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10.1016/j.pupt.2010.01.002 45 RheeJ.LeeK.KimD.LeeY.JeonO.KwonH.et al (2007)

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