The drug-free neutrally charged peptide, containing a cationic peptide guanidinium-functionalized poly(L-lysine) and a pH-sensitive peptide poly(ethylene glycol)-b-poly(-lysine)-graft-cyclohexene-1,2-dicarboxylic anhydride, exhibited similar efficacy against resistant MCF-7/ADR cells and MCF-7 cells in vitro (Yang et al., 2022)
M.GuptaA.GriffithS.NakeebA.ChoiJ
Researchers continue to investigate its biological activity across a range of experimental models
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Practical Advice To mitigate degradation, peptides should only be kept at room temperature when absolutely necessary, such as during short-term handling or transportation