GLP-1 is a highly sought after therapeutic target due to its beneficial effects on glucose homeostasis, particularly through regulation of beta cell mass, function, and viability
Minor side effects & safety profile While AOD 9604 appears to have a favorable tolerability profile in early trials, there are still relevant caution points: Reported/mild side-effects Injection-site reactions: redness, swelling, itching, mild pain
10.1016/j.lfs.2018.11.013 183 YamamotoS.LevinH
The risk may be increased if this product is used for an extended time, especially in newborns or in people with kidney disease
Genotype should be considered when attempting to predict the potential CYP2C9 drug-drug interactions because of the possible genotype-dependent inhibition (22,23)