Studies show that many users achieve significant weight reduction
In rodents, GLP-1 has been shown to increase the biosynthesis of glucose transporter 2 (GLUT-2) and glucokinase [29]
Sundaram ME, Meydani SN, Vandermause M, Shay DK, Coleman LA, Vitamin E
10.1073/pnas.80.3.707 3 BerkM.MalhiG
And importantly, clinicians should remain open to considering rare diagnoses like ROHHAD when the phenotype includes hypoventilation, autonomic dysregulation, or extreme hyperphagia. Perhaps one of the most exciting takeaways is that this patients hyperphagia improved markedly (and likewise quickly worsened during medication interruptions), suggesting that some of her hyperphagia was being modulated by GLP-1 RA therapy
Van Der Velpen et al., 2019