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The relationships of nutrients, routes of delivery, and immunocompetence

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The function of ROS can be either beneficial or damaging, depending on its cellular concentration and localization 2,3,4

However, the efficacy of topical glutathione can vary, as it may not penetrate deeply enough to deliver significant antioxidant benefits

Other Names for This Condition 5-oxoprolinemia 5-oxoprolinuria Deficiency of glutathione synthase Deficiency of glutathione synthetase Pyroglutamic acidemia Pyroglutamic aciduria Additional Information & Resources Genetic and Rare Diseases Information Center Patient Support and Advocacy Resources Clinical Trials Catalog of Genes and Diseases from OMIM Scientific Articles on PubMed References Al-Jishi E, Meyer BF, Rashed MS, Al-Essa M, Al-Hamed MH, Sakati N, Sanjad S, Ozand PT, Kambouris M

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