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The thermal program was as follows: initial denaturation at 98C for 3 min and 40 cycles (95C/10 s, 60C/30 s)

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The cell was treated with a medium that included 500 M H 2 O 2 solution that was treated with a variety of materials

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Graves disease can involve the thyroid exclusively or it can be associated with extrathyroidal manifestations, among which Graves orbitopathy is the most common

The advantages of this molecule are smaller size and greater penetration into solid tumors compared to conventional antibodies [143]