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In a placebo-controlled study that included 12 healthy volunteers, the application of dexpanthenol-containing ointment (every 12 hours for 1 to 6 days) in a model of skin wound healing was associated with an enhanced expression of markers of proliferation, inflammation, and tissue repair (26)

Clinicians consider dose, treatment length, and patient age when evaluating potential effects and risks before clinical use

Microscopically, balloon cell change consists of a partial or complete component of cells exhibiting abundant welldemarcated, clear to foamy cytoplasm containing a small benignappearing hyperchromatic nucleus

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The two work through different mechanisms and may produce additive benefits