Worth a read for anyone following obesity care and real-world evidence: To view or add a comment, sign in A diagnostic paradox buried in the Lancet obesity framework: Patient A: HbA1c 6.1% + dyslipidemia meets definition of "clinical obesity" Patient B: HbA1c 6.8% (diagnosed T2DM) + normal lipids may not qualify as "clinical obesity" T2DM was excluded from the organ-dysfunction criteria despite: ~90% of T2DM patients being overweight or obese Strong mechanistic links to visceral & ectopic fat ~50% diabetes remission rate with intensive weight loss at 1 year This inconsistency may create real coverage and access problems
doi:10.1371/journal.pone.0135268
The genus name is Greek from para , around, onyx , nail and the noun suffix -ia. 21 A quick search of the internet revealed that paronychia is also an affliction inflammation around fingernails or toenails resulting from trauma, irritation or infection
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11 For further reading on the extensive subject of G6PD deficiency, we refer the reader to excellent reviews.17,41,107,189 6-Phosphogluconate Dehydrogenase (Decarboxylating) (EC 1.1.1.44) Even though the oxidation of phosphogluconate to ribulose 5-phosphate by 6-phosphogluconate dehydrogenase generates one mole of NADPH, the few cases of 6-phosphogluconate dehydrogenase deficiency usually are not associated with hemolysis
