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The beneficial effects of GLP-1 RAs on HRQoL and other outcomes in HFpEF are likely due to pleiotropic impacts, related or not to weight reduction, such as decongestion (mainly due to the reduction of increased plasma volume associated with obesity and epicardial constrain), reverse cardiac remodelling (mainly due to the decrease in epicardial fat and regression of left atrial and LV myopathy, lowering intracardiac pressure) and anti-inflammatory actions, among others
Harvard Health Publishing: Study: Taking GLP-1 drugs may increase risk of key nutrient deficiencies
Retrieved from FDA Approves New Drug Treatment for Chronic Weight Management, First Since 2014
CJC-1295 / Ipamorelin avoids these risks by stimulating your body to release its own growth hormone in a physiologic rhythm, maintaining the natural feedback loop that helps keep hormones balanced
When your body is experiencing significant stress, your hair becomes stuck in that resting phase, she notes