The dose-corrected accumulation ratio ( R acc,DC ) was approximately 2, suggesting that, in healthy Chinese subjects, semaglutide accumulated as expected based on the t (~1 week) and dosing interval (1 week)
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Abbreviations GLP-1 RA: Glucagon-like peptide-1 receptor agonist MACE: Major adverse cardiovascular events HR: Hazard ratio CI: Confidence interval HER: Electronic health record ICD: International statistical classification of diseases and related health statistical classification of diseases and related health problems CPT: Current procedural terminology BMI: Body mass index MRA: Mineralocorticoid receptor antagonist ACE inhibitor: Angiotensin converting enzyme inhibitor ARB: Angiotensin II receptor blocker SGLT2 inhibitor: Sodium-glucose co-transporter 2 GFR: Glomerular filtration rate HbA1c: Hemoglobin A1c STROBE: Strengthening the reporting of observational studies in epidemiology SD: Standard deviation PS: Propensity score SMD: Standardized mean difference References Nichols, G
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Without the ability to swallow, saliva can enter the lungs and cause pneumonia
In a two-week timeframe, its plausible to observe initial changes in performance metrics (like endurance in animal models) and key metabolic biomarkers
