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Hydrogen specifically neutralizes only harmful hydroxyl radicals, and does not affect superoxide or hydrogen peroxide 8

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believe that, for melanotic lesions with an interval of fewer than 5 years with variations in size and shade or with bleeding and ulceration, the excision ought to be performed and lesions with no change in feature for five years or with an identified reason such as trauma can be periodically monitored

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9b) however many cases have no radiographic findings [14]