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Most notably, the highest dose of retatrutide (12 mg) led to 24.2% weight loss (vs 2.1% with placebo) at 48 weeks

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If you are self-administering your medication at home, we schedule follow-up appointments every 6 weeks either by phone or in personto monitor your progress, address any concerns, and ensure your treatment is safe and effective

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Currently, Eli Lilly's GLP-1 weight-loss and diabetes drugs, Mounjaro (tirzepatide) and Zepbound (tirzepatide) are the global leaders, with combined 2025 revenue exceeding $36.5 billion and accounting for over 56% of the company's total revenue