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If someone with a known B12 deficiency develops persistent anemia, elevated white blood cell (WBC) counts, or noticeable lymph node enlargement, it is important to consider the possibility of an underlying hematologic malignancy and seek prompt medical evaluation

Since SLS and DLS provide complementary information on protein size, shape, and aggregation state, these techniques are commonly used together

Kuzminski AM, del Giacco EJ, Allen RH et al (1998) Effective treatment of cobalamin deficiency with oral cobalamin

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Research has explored iontophoresis, microneedle delivery, and specialized cream formulations to improve transdermal delivery

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