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doi: 10.1155/2022/5299218 [DOI] [PMC free article] [PubMed] [Google Scholar] 90

The FDA also recently approved the use of some of these drugs for the treatment of heart diseasespecifically, for the reduction of adverse cardiovascular events such as heart attacks

More than a decade ago, concerns about the CV safety of new glucose-lowering agents led the FDA to request that all new agents demonstrate no additional CV risk with their use

Mutagenesis 2006

Matsuno Y, et al

Study participants reported a median body mass index (BMI) of 35.1 kg m 2 before initiating GLP1 treatment, with 96.8% of participants having a BMI of at least 25 at baseline