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The B class of GPCRs is a relatively small group of receptors but, nevertheless, one that is important in metabolic diseases such as diabetes and obesity (62)

Melanocortin receptor ligands: new horizons for skin biology and clinical dermatology. J Invest Dermatol

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2.2 Parkinson's disease (PD) PD patients show exhaustive gut microbiome dysbiosis, such as reduced Prevotella and increased Enterobacteriaceae, which can be related to GI symptoms such as constipation (Hashish and Salama, 2023)