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Firstly, the facile modification of two therapeutics with distinctly different properties onto a single cell-based carrier remains a challenging task 51,52

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Advances in high-throughput sequencing and bioinformatics have provided deeper insights into the composition and function of the microbiome, as well as its interactions with host health and disease

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Additionally, clearance of these particles from the bloodstream (via the liver and spleen) is inversely related to size: the smallest particles circulate the longest, increasing the likelihood of absorption at their target tissues