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The diagnosis of dementia was made according to the criteria of the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition.17 Only persons with a duration of symptoms longer than 6 months and a score for severity of dementia of 1 or higher on the Clinical Dementia Rating Scale were considered incident cases.18 Patients with suspected cognitive deficits for whom definite dementia could not be established underwent annual reassessment

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For example, other antidiabetic agents (such as insulin, metformin, glyburide, sitagliptin, and canagliflozin) taken along with GLP-1 RAs potentiate hypoglycemic risk and may necessitate dose adjustments