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High-affinity binding of celastrol to monomeric -synuclein mitigates in vitro aggregation

Cancelled Phase I Trial: A 2015 Phase I study with 42 volunteers was registered, but the results were never published, and no public explanation was provided

Monosynaptic initiation of the inhibitory postsynaptic potentials

These targets include TNF-, IL-1, IL-6, and IL-8 [74]

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just 10% of patients who received granulocyte-CSF with placebo reached a similar level of stem cell mobilization