Adv Mater, 2020, 32: 2004460 He X, Sathishkumar G, Gopinath K, et al
Abbreviations CVD: Cardiovascular disease HF: Heart failure HFrEF: Heart failure with reduced ejection fraction IV: Intravenous ID: Iron deficiency TSAT: Transferrin saturation FCM: Ferric carboxymaltose DCYTB: Duodenal cytochrome B CRT: Cardiac resynchronization therapy CMR: Cardiac magnetic resonance ROS: Reactive oxygen species ATP: Adenosine triphosphate Fe: Iron FPN: Ferroportin sTfR: Soluble transferrin receptor TIBC: Total iron-binding capacity HIF: Hypoxia-inducible factor IL: Interleukin eNOS: Endothelial nitric oxide synthase HFE: Hemochromatosis gene AHA: American Heart Association ACC: American College of Cardiology HFSA: Heart Failure Society of America ESKD: End-stage kidney disease References WHO
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BBR stabilizes LDLR expression by reducing the affinity between hnRNP I or KSRP and LDLR (Singh et al., 2014
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Immune system and G6PD-deficiency ASCVD is a chronic inflammatory disease mediated by both the innate and adaptive arms of the immune system