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Among the current options, Wegovy can help people lose an average of 10 percent of their body weight in a year, while people taking Zepbound have had about a 15 percent loss, on average, in the same period

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The absence of visible problems does not guarantee the peptide is still potent

The main drivers for weight regain after significant WL include the persistence of a lower resting metabolic rate and the increased appetite, possibly mediated through long lasting increased orexigenic and decreased anorexigenic signals [2, 6]