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Long-lasting effects One injection lasts 4-6 weeks, so patients only need injections every month or two for maintenance

Another mechanism by which antioxidant micronutrients can block H.pylori -induced FR production resides in their ability to augment the bodys immune response against this pathogen either by enhancing the humoral and cell-mediated immunity [59], increasing blood B- and T-lymphocytes [60], promoting lymphocyte proliferation and neutriophil's phagocytic activity in addition to a significant reduction of macrophage-induced superoxide anion production [61]

To make that determination they would have needed groups who stayed at the various levels over time because its possible that those same gains would have been seen even if they hadn't titrated up

Psychiatry Neurosci

Gorio A, Di Giulio AM, Tenconi B, et al

its theoretical advantage (physiological sleep architecture modulation without sedation) has not been confirmed by adequately powered trials