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8,9 Manifestations Vitamin B 12 deficiency affects multiple systems, and sequelae vary in severity from mild fatigue to severe neurologic impairment 1,2,6,10 (Table 2 4,10 )

They follow strict diets and exercise regimens but still find it nearly impossible to lose weight

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This catalytic cascade culminates in the production of superoxide anions

Although classical antioxidant drugs failed in clinical trials against neurodegenerative disorders 28 , mito GCL, by acting as a persistent antioxidant source for mitochondria, may represent a new gene therapy strategy to improve the transient efficacy of the formers

Dietary BCAA intake is quantified through food frequency questionnaires, 24-h dietary recalls, or weighed food records, each presenting distinct measurement error profiles